The 1999–2000 network television schedule for the six major English language commercial broadcast networks in the United States covers primetime hours from September 1999 through August 2000.
PBS is not included; member stations have local flexibility over most of their schedules and broadcast times for network shows may vary.
Each of the 30 highest-rated shows is listed with its rank and rating as determined by Nielsen Media Research.
On Fox, Manchester Prep was supposed to air at 8–9, but it was cancelled at the last minute.
On ABC, Then Came You was scheduled to air at 8:30 PM EST, but due to the show not getting the "buzz" before the fall premiere, Whose Line Is It Anyway?