The season began on November 2, 1999, and ended with the Los Angeles Lakers winning the NBA championship, beating the Indiana Pacers 4 games to 2 in the 2000 NBA Finals.
Notes Teams in bold advanced to the next round.
The division champions are marked by an asterisk.
Home court advantage does not necessarily belong to the higher-seeded team, but instead the team with the better regular season record; teams enjoying the home advantage are shown in italics.
The following players were named the Rookies of the Month.