The 1999 Adidas Open de Toulouse was a men's tennis tournament played on indoor hard courts in Toulouse, France that was part of the World Series of the 1999 ATP Tour.

It was the eighteenth edition of the tournament and was held from 27 September until 3 October 1999.

Unseeded Nicolas Escudé won the singles title.

[3] Nicolas Escudé defeated Daniel Vacek, 7–5, 6–1 Olivier Delaître / Jeff Tarango defeated David Adams / John-Laffnie de Jager, 3–6, 7–6, 6–4