1999 Grand Prix motorcycle racing season

The dominant reign of Honda's Mick Doohan came to an end with serious injuries suffered in practice for the Spanish Grand Prix.

[1] In his absence, his Honda teammate Àlex Crivillé stepped forward and claimed Spain's first-ever 500cc world championship.

[1] A young Valentino Rossi continued to impress for Aprilia, winning nine races and claiming his second world championship, this time in the 250 class.

Bold – Pole positionItalics – Fastest lap [6] Points were awarded to the top fifteen finishers.

Bold – Pole positionItalics – Fastest lap [7] Points were awarded to the top fifteen finishers.