The 1999 McNeese State Cowboys football team was an American football team that represented McNeese State University as a member of the Southland Conference (Southland) during the 1999 NCAA Division I-AA football season.
In their first year under head coach Kirby Bruchhaus, the team compiled an overall record of 6–5, with a mark of 5–2 in conference play, and finished third in the Southland.
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