The 1999 Tashkent Open was a women's tennis tournament played on hard courts at the Tashkent Tennis Center in Tashkent, Uzbekistan that was part of the Tier IVb category of the 1999 WTA Tour.

It was the inaugural edition of the tournament and was held from 7 June through 13 June 1999.

First-seeded Anna Smashnova won the singles title and earned $16,000 first-prize money.

Anna Smashnova defeated Laurence Courtois, 6–3, 6–3 Evgenia Kulikovskaya / Patricia Wartusch defeated Eva Bes / Gisela Riera, 7–6(7–3), 6–0 The following players received wildcards into the singles main draw: The following players received wildcards into the doubles main draw: The following players received entry from the singles qualifying draw: The following players received entry from the doubles qualifying draw: