The 1999 Welsh Open (officially the 1999 Regal Welsh Open) was a professional ranking snooker tournament that took place between 25 and 31 January 1999 at the Cardiff International Arena in Cardiff, Wales.

Paul Hunter was the defending champion, but he lost his last 32 match against Fergal O'Brien.

Mark Williams defeated Stephen Hendry 9–8 in the final to win his fifth ranking title.

The remaining places were allocated to players based on the world rankings.

Ronnie O'Sullivan made a maximum break during the third frame of his quarter final victory over James Wattana.