The Men's 4 × 400 metres relay event at the 1999 World Championships in Athletics was held at the Estadio Olímpico de Sevilla on August 28 and August 29.
After Antonio Pettigrew later admitted to taking banned substances, the winning US team was retrospectively disqualified.
All times shown are in minutes.
Botswana (Rampa Mosweu, Lulu Basinyi, California Molefe, Johnson Kubisa) DQ Nigeria (Udeme Ekpeyong, Jude Monye, Fidelis Gadzama, Sunday Bada) DQ Hungary (Péter Nyilasi, Balázs Korányi, Zsolt Szeglet, Tibor Bédi) DNF United States (Jerome Davis, Antonio Pettigrew, Angelo Taylor, Michael Johnson) DQ