[11] In 2014 he was awarded an honorary degree by the University of Brighton in his home county East Sussex in recognition for his "contribution to business, entrepreneurship and philanthropy".

He started his own management company in 1985, 19 Entertainment,[16] eventually selling the business to CKX, Inc. in a cash and stock deal worth over $200 million in March 2005.

[18] Fuller became a director of CKX, a position which gave him creative control over all of CKX's assets including the Elvis Presley Estate, Muhammad Ali's business interests, and other rights properties, until January 2010 when he started a new firm, XIX Entertainment, while continuing to work with CKX/19 as a consultant and executive producer.

Fuller's first broadcast venture was Miami 7, a scripted TV drama starring the British pop group S Club 7 screened by BBC/Fox Kids in 100+ territories around the world.

[23] In 2001, Fuller created Pop Idol, a prime time TV show on British television that Maggie Brown in The Guardian states "became a seminal reality/entertainment format".

[29] In 2012, Simon Fuller's XIX Entertainment created a new international format with Jennifer Lopez, Marc Anthony, and Jamie King named Q'Viva!

[31][32] In 2017, international news media reported on auditions being staged by Fuller's business XIX for Now United, a real time access global pop group being cast in 14 cities around the world.

[38] He has managed acts including Victoria Beckham, Annie Lennox, S Club 7, S Club Juniors, Now United, Steven Tyler, Amy Winehouse, Carrie Underwood, Kelly Clarkson, Will Young, Emma Bunton, Any Gabrielly, The Future X, Lisa Marie Presley and many more in addition to sports icons Lewis Hamilton and Andy Murray.

[40] He has managed hit songwriters and producers, including Cathy Dennis, who first met Fuller as the singer of D Mob in the 1980s.

1 female songwriter with a string of hits for artists including Kylie Minogue, Britney Spears, Katy Perry, Pink, Will Young, and others.

[42][43] Under Fuller's guidance, the Spice Girls became a marketing phenomenon, rose to chart topper status worldwide and went on to sell over 85 million records.

[44][45] In 2002, Fuller's company discovered 19-year-old Amy Winehouse, produced her first award-winning album Frank and signed her to Universal Music.

[48] In 2025 Fuller's longterm partnership with Nick Shymansky's Day One Music management company led to a UK No.1 ands global hit for Lola Young.

In 2008, after assembling a highly qualified creative team Fuller launched the Victoria Beckham dress collection at New York Fashion Week.

[54] The first result of this partnership was the Fall 2016 re-launch of the British heritage menswear label Kent & Curwen, which under Beckham, Fuller and 7 Global ownership currently runs 113 stores in 51 cities worldwide.

In 2014, Fuller was awarded an honorary degree by the University of Brighton in recognition for his "contribution to business, entrepreneurship and philanthropy".