[1] In September 1915, the 2nd Division was despatched to the Gallipoli Peninsula as reinforcements, and after this the battalion saw their first action after relieving elements of the 2nd Brigade holding positions north of Anzac Cove, allowing them to be withdrawn for rest.

The 22nd remained at Gallipoli until the final evacuation took place in December 1915, primarily undertaking defensive duties.

[1] After being withdrawn back to Egypt, the battalion was strengthened by reinforcements from Australia as the AIF's infantry divisions were reorganised and expanded before being sent to France to take part in the fighting on the Western Front.

The battle proved a very costly introduction to the Western Front for the 22nd Battalion, with their losses between 25 July and 7 August 1916 totalling 27 officers and 656 other ranks killed or wounded.

[1] The fighting around Montbrehain, which took place on 5 October 1918, was the final action fought by Australian infantrymen on the Western Front during the war, and came as part of a series of attacks made by the Allies to breach the Hindenburg Line following the launch of the Hundred Days Offensive.

The two units were split in August 1939 as the Australian military was expanded just prior to the outbreak of World War II.

[11] Early in the war, the 22nd was assigned to the 4th Brigade and undertook garrison duties and training camps in Australia – based mainly in Queensland.

The battalion initially deployed to the Milne Bay area in March 1943 undertaking garrison duties and jungle training before moving to Lae shortly after its capture by Australian forces in early September.

[12] This feat was described by the Kalgoorlie Miner as the "greatest march" of the New Guinea campaign and in 10 days the battalion covered 50 miles (80 km) of rugged terrain.

[11] After a total of 16 months overseas, the battalion was withdrawn back to Australia for rest and reorganisation in September 1944.

[11] In 1966, following the reintroduction of national service, the 22nd Battalion was re-raised as part of the Royal Victoria Regiment, as a remote area battalion within the Citizens Military Force, offering special conditions of service for those eligible for call up who elected to serve in the CMF rather than the Regular Army, but who could not meet their training requirements through normal attendance due to their occupation or place of residence.