The 2000–01 Eredivisie season was contested by 18 teams.

PSV won the championship.

In the promotion/relegation competition, eight entrants (six from the Eerste Divisie and two from this league) entered in two groups.

The group winners were promoted to (or remained in) the Eredivisie.

Feyenoord drew the highest average home attendance in the 2000-01 edition of the Eredivisie.