The 2000–01 NCAA Division I men's ice hockey season began on October 6, 2000 and concluded with the 2001 NCAA Division I Men's Ice Hockey Tournament's championship game on April 7, 2001 at the Pepsi Arena in Albany, New York.

The U.S. College Hockey Online poll was voted on by coaches, media, and NHL scouts.

Note: * denotes overtime period(s) [2] The following players led the league in points at the conclusion of the season.

GP = Games played; G = Goals; A = Assists; Pts = Points; PIM = Penalty minutes [3] The following goaltenders led the league in goals against average at the end of the regular season while playing at least 33% of their team's total minutes.

GP = Games played; Min = Minutes played; W = Wins; L = Losses; OT = Overtime/shootout losses; GA = Goals against; SO = Shutouts; SV% = Save percentage; GAA = Goals against average [3]