The thirty-seven teams of the North, South, East, and West divisions competed in a 49-game schedule.
Come February, the top eight teams of each division competed for the Frank L. Buckland Trophy, the OPJHL championship.
The Rattlers were not successful in winning the 2001 Royal Bank Cup.
Note: GP = Games played; W = Wins; L = Losses; OTL = Overtime losses; SL = Shootout losses; GF = Goals for; GA = Goals against; PTS = Points; x = clinched playoff berth; y = clinched division title; z = clinched conference title Division Quarter-final Division Semi-final Division Final Semi-final Final Best-of-7 Hosted by Flin Flon Bombers in Flin Flon, Manitoba.
[2] Round Robin Note: GP = Games played; G = Goals; A = Assists; Pts = Points; PIM = Penalty minutes