The 2000–01 Southern Utah Thunderbirds men's basketball team represented Southern Utah University in the 2000–01 NCAA Division I men's basketball season.

The Thunderbirds, led by 5th-year head coach Bill Evans, played their home games at the America First Event Center in Cedar City, Utah as members of the Mid-Continent Conference.

They defeated Western Illinois, Oral Roberts, and Valparaiso to win the Mid-Con tournament and receive the conference's automatic bid to the NCAA tournament – the first, and only, appearance in program history.

14 seed in the East region, the Thunderbirds were beaten by No.

3 seed Boston College in the opening round.