After winning the Presidents' Trophy the previous season, the Blues finished the regular-season with a record of 43 wins, 22 losses, 12 ties and 5 overtime losses, enough for 103 points and a trip to the 2001 Stanley Cup playoffs.
In the Western Conference Quarterfinals, the Blues defeated the San Jose Sharks in six games, then swept the Pacific Division-winning Dallas Stars in the Conference Semifinals before losing in five games to the eventual Stanley Cup champion Colorado Avalanche in the Conference Finals.
Note: CR = Conference rank; GP = Games played; W = Wins; L = Losses; T = Ties; OTL = Overtime loss; GF = Goals for; GA = Goals against; Pts = Points Bolded teams qualified for the playoffs.
Divisions: CEN – Central, PAC – Pacific, NW – Northwest bold – Qualified for playoffs; p – Won Presidents' Trophy; y – Won division
Win (2 points) Loss (0 points) Tie (1 point) Overtime loss (1 point) Win Loss The Blues were involved in the following transactions from June 11, 2000, the day after the deciding game of the 2000 Stanley Cup Finals, through June 9, 2001, the day of the deciding game of the 2001 Stanley Cup Finals.