The Owen Sound Platers were renamed to the Owen Sound Attack Twenty teams each played 68 games.
The Ottawa 67's won the J. Ross Robertson Cup, defeating the Plymouth Whalers.
Note: DIV = Division; GP = Games played; W = Wins; L = Losses; T = Ties; OTL = Overtime losses; GF = Goals for; GA = Goals against; PTS = Points; x = clinched playoff berth; y = clinched division title; z = clinched conference title Defencemen Wingers Centres On May 5, 2001, the OHL conducted the 2001 Ontario Hockey League Priority Selection.
The Mississauga IceDogs held the first overall pick in the draft, and selected Patrick O'Sullivan from the USA U17 team.
Below are the players who were selected in the first round of the 2001 Ontario Hockey League Priority Selection.