The 2000 Coca-Cola 600 was the 12th stock car race of the 2000 NASCAR Winston Cup Series and the 41st iteration of the event.

The race was held on Sunday, May 28, 2000, before an audience of 183,500 in Concord, North Carolina, at Charlotte Motor Speedway, a 1.5 miles (2.4 km) permanent quad-oval.

The complex features a1.5 miles (2.4 km) quad oval track that hosts NASCAR racing including the prestigious Coca-Cola 600 on Memorial Day weekend and the NEXTEL All-Star Challenge, as well as the UAW-GM Quality 500.

The speedway was built in1959 by Bruton Smith and is considered the home track for NASCAR with many race teams located in the Charlotte area.

Melling Racing's Stacy Compton set the fastest time in the session, with a lap of 30.189 and an average speed of 178.873 mph (287.868 km/h).

Penske-Kranefuss Racing's Rusty Wallace set the fastest time in the session, with a lap of 30.438 and an average speed of 177.410 mph (285.514 km/h).

Joe Gibbs Racing's Bobby Labonte set the fastest time in the session, with a lap of 30.175 and an average speed of 178.956 mph (288.002 km/h).