The 2000 South American Cross Country Championships took place on February 5–6, 2000.

The races were held in Cartagena de Indias, Colombia, jointly with the Central American and Caribbean Cross Country Championships.

[1] †: Athlete marked as guest, but accounted for team score.

†: Athlete marked as guest, but accounted for team score.

According to an unofficial count, 86 athletes from 9 countries were competing for the Central American and Caribbean Cross Country Championships.