2001 Holy Cross Crusaders football team

In their sixth year under head coach Dan Allen, the Crusaders compiled a 4–6 record.

Brian Hall, James Jenkins and Vernell Shaw were the team captains.

Holy Cross' 3–4 conference record placed fifth out of eight in the Patriot League standings.

[2] Like most of the Patriot League, Holy Cross played just 10 of its 11 scheduled games, after its September 15 matchup, against Ivy League opponent Harvard, was canceled following the September 11 attacks.

Holy Cross played its home games at Fitton Field on the college campus in Worcester, Massachusetts.