Floyd Spence Republican Joe Wilson Republican The 2001 South Carolina 2nd congressional district special election was held on December 18, 2001, to select a Representative for the 2nd congressional district to serve out the remainder of the term for the 107th Congress.

Joe Wilson, a state senator from Lexington County and a former aide to Spence, won the Republican primary and went on to win the general election against Democratic challenger Brent Weaver.

The Republican Party was on the rise in South Carolina and there was a great deal of enthusiasm among its voters.

Additionally, the 2nd had long been a Republican stronghold; it had been in GOP hands without interruption since a 1965 special election.

As expected, Wilson scored a decisive victory in the general election and he was sworn into Congress the very next day.