The 2001 Western Kentucky Hilltoppers football team represented Western Kentucky University in the 2001 NCAA Division I-AA football season and were coached by Jack Harbaugh.

[1] They qualified for the NCAA Division I-AA Playoffs where they were defeated by eventual runner-up, Furman.

[3] This team included future NFL players Joseph Jefferson, Mel Mitchell, Sherrod Coates, and Brian Claybourn.

Mitchell, Eric Dandy, and Chris Price were named to the AP All American team and Jefferson was selected to play in the Blue-Gray Football Classic.

The All-Conference team included Coates, Dandy, Jefferson, Mitchell, Price, Patrick Reynolds, Buster Ashley, Claybourn, Peter Martinez, Kyle Moffatt, and Daniel Withrow.