The 16th Annual Nickelodeon Kids' Choice Awards was held on April 12, 2003, hosted by Rosie O'Donnell.

By this point, she had hosted the awards seven times in a row.

The announcers were Daran Norris and Susanne Blakeslee from The Fairly OddParents, in character as Cosmo and Wanda, respectively, for the event.

Justin Timberlake highlighted the show by performing his hit "Rock Your Body".

Later, B2K performed a "That Girl"/"Girlfriend" medley with Marques Houston.