The 2004–05 Delaware State Hornets men's basketball team represented Delaware State University during the 2004–05 NCAA Division I men's basketball season.

The Hornets, led by head coach Greg Jackson, played their home games at Memorial Hall and were members of the Mid-Eastern Athletic Conference.

They defeated Bethune-Cookman, South Carolina State, and Hampton to win the MEAC tournament and secure the conference's automatic bid to the NCAA tournament – the first, and only, appearance in school history.

16 seed in the South region, the Hornets were beaten by No.

1 seed Duke in the opening round.