The competition started on 10 September 2004 and concluded on 21 May 2005 with the Greek Cup final, held at the Pampeloponnisiako Stadium.
Olympiacos earned the trophy with a 3–0[1] victory over Aris.
Each tie in the knockout phase, apart from the final, was played over two legs, with each team playing one leg at home.
The team that scored more goals on aggregate over the two legs advanced to the next round.
If the aggregate score was level, the away goals rule was applied, i.e. the team that scored more goals away from home over the two legs advanced.
If away goals were also equal, then extra time was played.
The away goals rule was again applied after extra time, i.e. if there were goals scored during extra time and the aggregate score was still level, the visiting team advanced by virtue of more away goals scored.
If no goals were scored during extra time, the winners were decided by a penalty shoot-out.
In the final, which were played as a single match, if the score was level at the end of normal time, extra time was played, followed by a penalty shoot-out if the score was still level.The mechanism of the draws for each round is as follows: Panathinaikos won 7–2 on aggregate.
Ethnikos Piraeus won on away goals.
Poseidon Neon Poron did not show up.
[2] Poseidon Neon Poron did not show up.
Apollon Kalamarias won on away goals.
Chalkidon Near East won on extra time.
Apollon Kalamarias won away goals.