The 2004 Wyoming Cowboys football team represented the University of Wyoming in the 2004 NCAA Division I-A football season.

Led by head coach Joe Glenn, the Cowboys competed in the Las Vegas Bowl.

During the off season, War Memorial Stadium was upgraded with new railings installed in certain areas as well as more handicap accessible.

[1] The big concern coming into Spring Training was the lack of depth on defense, a young and inexperienced offensive line and a poor running game.

[4] Corey Bramlet replaced his older brother, Casey, who graduated the previous season.