The 2005–06 Bradley Braves men's basketball team represented Bradley University as a member of the Missouri Valley Conference during the 2005–06 NCAA Division I men's basketball season.

Led by head coach Jim Les, the Braves finished the season with a 22-11 record (11-7 MVC).

They earned an at-large bid to the NCAA tournament as #13 seed in the Oakland Regional.

The team defeated Kansas and Pittsburgh to reach the Sweet Sixteen, before falling to Memphis in the regional semifinal.

Sources: [2] [6] [7]