The 2005–06 Cleveland State Vikings men's basketball team represented Cleveland State University in the 2005–06 college basketball season.
The team was led by third-year head coach Mike Garland.
The win against Rochester College raised CSU's all-time record in the building to 123–21.
The preseason Horizon League Coaches' Poll picked the Vikings to finish eighth.
Raheem Moss was named to the preseason all-Horizon League 2nd team.