The 2005–06 Combined Counties Football League season was the 28th in the history of the Combined Counties Football League, a football competition in England.
The Premier Division featured one new team in a league of 22 teams after the promotion of Walton Casuals to the Isthmian League.
Also:
Division One featured four new teams in a league of 17 teams: Also, Netherne Village changed their name to Netherne.