The 2005–06 Euroleague was the 6th season of the professional basketball competition for elite clubs throughout Europe, organised by Euroleague Basketball Company, and it was the 49th season of the premier competition for European men's clubs overall.

The Final Four was held at the Sazka Arena in Prague, Czech Republic on April 30, 2006.

CSKA Moscow defeat the defending champions, Maccabi Elite by a score of 73–69 in the final.

The complete list of tiebreakers was provided in the lead-in to the Regular Season results.

If one or more clubs were level on won–lost record, tiebreakers were applied in the following order: 3–5 are used to break ties between 6th place teams