The 2005–06 Greek Basket League season was the 66th season of the Greek Basket League, the highest tier professional basketball league in Greece.

The winner of the league was Panathinaikos, which beat Olympiacos in the league's playoff's finals.

The teams Iraklis and Kolossos Rodou were relegated to the Greek A2 League.

Pts=Points, P=Matches played, W=Matches won, L=Matches lost, F=Points for, A=Points against, D=Points difference Panathinaikos win the series 2-0 Olympiacos win the series 2-0 Maroussi win the series 2-1 Aris win the series 2-0 Panathinaikos win the series 3-0 Olympiacos win the series 3-2 Aris win the series 3-2 Panathinaikos win the series 3-0 Game 1Game 2Game 3Points Rebounds Assists Steals Blocks Source: Galanis Sports Data Archived 2008-02-23 at the Wayback Machine Points Rebounds Assists Steals Blocks Source: Galanis Sports Data Archived 2008-02-19 at the Wayback Machine