The 2005–06 Kansas Jayhawks men's basketball team represented the University of Kansas Jayhawks for the NCAA Division I men's intercollegiate basketball season of 2005–06.

The team played its home games in Allen Fieldhouse in Lawrence, Kansas.

In 2005–06 the Jayhawks fielded one of the youngest teams in the nation, by the end of the year the starting line-up consisted of 3 Freshmen and 2 Sophomores.

In postseason play the team defeated its conference opponents to claim its first Big 12 Championship title since 1999.

In the NCAA Division I tournament, the fourth-seeded Jayhawks were defeated in the first round by Bradley, a 13 seed.