The 2005–06 Los Angeles Clippers season was their 36th season in the NBA and their 22nd in Los Angeles.
[1] The Clippers finished with 47 wins and 35 losses in the regular season for their first winning season since 1991-92. their best record since the 1974–75 season when they were the Buffalo Braves and made the playoffs for the first time since 1997 as the 6th seed, finishing with a better record than their crosstown rival, the Los Angeles Lakers, who finished two games behind them with a 45–37 record as the 7th seed, for the first time since 1992.
In the playoffs, the Clippers defeated the 3rd seeded Denver Nuggets in the First Round in five games, marking the first time they won a series since moving to California in 1978.
The Clippers then advanced to the Semi-finals, where they lost in seven games to the Phoenix Suns.
The Suns previously defeated the Clippers' Staples Center co-tenants, the Los Angeles Lakers, in seven games in the First Round after being down 1–3 in the series.