The 2005–06 Mid-American Conference women's basketball season began with practices in October 2005, followed by the start of the 2005–06 NCAA Division I women's basketball season in November.
Bowling Green won the regular season title with a record of 16–0 by one game over West Division champion Eastern Michigan.
Lindsay Shearer of Kent State shared MAC player of the year.
[1] Regular season champion Bowling Green won the MAC tournament over Kent State.
[6] (First place votes in parentheses) Bowling Green (15), Kent State (5), Eastern Michigan (4), Western Michigan (1) [7] [1] [8] 2005–06 Mid-American Conference men's basketball season