The 2005–06 Oral Roberts Golden Eagles men's basketball team represented Oral Roberts University during the 2005–06 NCAA Division I men's basketball season.

The Golden Eagles, led by 7th year head coach Scott Sutton, played their home games at the Mabee Center and were members of Mid-Continent Conference.

They finished the season 21–12, 13–3 in league play to be crowned regular season champions.

They won the Mid-Continent Conference tournament to receive an automatic bid to the NCAA tournament as No.

1 seed Memphis in the opening round.