Porto and Sporting CP were both qualified for the 2005–06 UEFA Champions League group stage, and Benfica qualified for the UEFA Champions League qualifying round; Braga, Nacional and Vitória de Setúbal qualified for the 2006–07 UEFA Cup; in opposite, with the league dropping to 16 teams, four teams were relegated to the Liga de Honra; Gil Vicente, Rio Ave, Vitória de Guimarães and Penafiel.
The first yellow card of the season was given to Sporting's Fábio Rochemback in the opening game of the season, and the first red card was given to Benfica's João Pereira in his club's away draw against Académica de Coimbra.
Moreirense, Beira-Mar and Estoril were relegated to the Liga de Honra following their final classification in 2004–05 season.
The Footballer of the Year award was won by the Portuguese Ricardo Quaresma of Porto, for a second successive season.
The Portuguese Golden Shoe award was won by the Cameroonian Albert Meyong of Belenenses, scoring 17 goals.