The season began on 28 September 2005 with the Tour of Milad du Nour and ended on 16 September 2006 with the 2006 Asian Cycling Championships.

The points leader, based on the cumulative results of previous races, wears the UCI Asia Tour cycling jersey.

Andrey Mizurov from Kazakhstan was the defending champion of the 2005 UCI Asia Tour.

Ghader Mizbani of Iran was crowned as the 2005–06 UCI Asia Tour champion.

The quality and complexity of a race also determines how many points are awarded to the top finishers, the higher the UCI rating of a race, the more points are awarded.