The 2005–06 ULEB Cup was the fourth season of the second-tier level European professional club basketball competition, the EuroCup.

The EuroCup is the European-wide league level that is one tier below the EuroLeague level.

Dynamo Moscow won the trophy, by defeating Aris TT Bank in the final, by a score of 73–60.

April 11, Spiroudome, Charleroi