Argentina drew one of the most difficult groups in the 2006 FIFA World Cup, advanced to the second round but lost against hosts Germany in the quarter-finals.

After an abysmal season, Instituto and Tiro Federal were relegated to the Nacional B Division a few weeks before the end of the tournament.

The next two worst teams in the relegation standings, Argentinos Juniors and Olimpo de Bahía Blanca, played a Promoción playoff (home and away) series against Huracán and Belgrano de Córdoba, respectively, for two spots in next year's Argentine First Division.

Argentinos Juniors remains in the Argentine First Division after a 3 - 3 aggregate tie by virtue of a "sports advantage".

Belgrano de Córdoba wins 4-2 and is promoted to Argentine First Division.