It consisted of the Reds finishing in fifth place in the National League Central and failing to improve on their 76–86 record from 2004.
The Reds were managed by Dave Miley for most of the season, and after being fired, was followed by Jerry Narron.
The Reds missed the playoffs for the tenth straight season, tying a record set between 1980 and 1989.
The Reds finished with an overall record of 73–89, 16 games under .500, and in 5th place behind the division winner, the St. Louis Cardinals.
Infielders Coaches Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.