The 2005 IPSC Handgun World Shoot XIV held in Guayaquil, Ecuador was the 14th IPSC Handgun World Shoot.

Once again, Eric Grauffel took the Open title.

The Open division had the largest match participation with 300 competitors (33.8 %).

The Standard division had the second largest match participation with 294 competitors (33.1 %).

The Production division had the third largest match participation with 213 competitors (24.0 %).