The 2005 Women's World Open Squash Championship is the women's edition of the 2005 World Open, which serves as the individual world championship for squash players.

The event took place in Hong Kong from 29 November to 4 December 2005.

Nicol David won her first World Open trophy, beating Rachael Grinham in the final.

In 2005, the points breakdown were as follows: Note: * Q = Qualifier, * w/o = Walkover, * r = Retired [1]