The championship was decided in the penultimate round on May 12, 2007, when Anderlecht moved five points clear of runners-up Genk to retain the title and win their 29th League Championship.
At the other end of the table, the struggle to avoid automatic relegation went on until the final round, and it was Lierse who eventually prevailed.
Having spent the entire season at the bottom of the standings and only just managing to close an eleven-point gap up to 17th, the Lier side won their last game to climb past Beveren and send the latter down to the Second Division.
La Louvière had been relegated at the end of the previous season with Mons replacing them as they won the Belgian Second Division.
Lierse had managed to win the promotion playoff and thus they remained in the first division.