The 2006–07 South Alabama Jaguars basketball team represented the University of South Alabama during the 2006–07 NCAA Division I men's basketball season.

The Jaguars were led by head coach John Pelphrey, in his fifth season as head coach.

They played their home games at the Mitchell Center, and were members of the Sun Belt Conference.

They finished the season 20–12, 13–5 in Sun Belt play to finish in first place.

They were invited to play in the NIT tournament, but lost in the first round against Syracuse.