During the 2006–07 Spanish football season, Valencia CF competed in La Liga, the Copa del Rey and the UEFA Champions League.

Valencia made significant changes for the season, with coach Quique Sánchez Flores and technical director Amedeo Carboni overhauling the squad.

Players who did not fit in the current playing system, such as Marco Di Vaio, Bernardo Corradi, Pablo Aimar, Rufete, and Mista, were some of those who were sold, while Fábio Aurélio signed for Liverpool (reuniting with former Valencia manager Rafael Benítez) after refusing an extension to his contract.

This poor run was attributed to injuries to key players like captain David Albelda, midfielder Rubén Baraja, wingers Jaime Gavilán and Vicente, defenders Carlos Marchena and Asier del Horno and forward Francesco Tavano.

Despite all these worries, the team is made a strong comeback, winning their last three matches before the winter break (against Deportivo de La Coruña, Real Zaragoza and Mallorca).