The 2006–07 Vyshcha Liha season is the sixteenth since its establishment.
The season started on July 21, 2006, with the game in Kyiv, Dynamo - Chornomorets 4:1.
The winner of the championship was declared Dynamo Kyiv acquiring their record-extending 12th title defeating the reigning champion Shakhtar Donetsk, who were the two-time defending champions.
Illichivets was forced into relegation for the first time since entering the League 10 years ago.
The game Karpaty-Metalist finished with a technical loss awarded to Lviv's club for no appearance.