This was head coach Gregg Marshall's ninth and final season at Winthrop.

The Eagles competed in the Big South Conference and played their home games at Winthrop Coliseum.

They won the 2007 Big South Conference men's basketball tournament to receive the conference's automatic bid to the 2007 NCAA Division I men's basketball tournament as No.

The Eagles defeated Notre Dame in the first round – the Big South’s first win in NCAA Tournament play[1] – before falling to No.

After the season, Marshall left to take over as head coach at Wichita State.