The 2006 İstanbul Cup was a women's tennis tournament played on outdoor clay courts.

It was the second edition of the İstanbul Cup, and part of the WTA Tier III tournaments of the 2006 WTA Tour.

Fourth-seeded Shahar Pe'er won the singles title.

* per team 1 Rankings as of 15 May 2006 The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: 1 Rankings as of 15 May 2006 The following pair received entry from the qualifying draw: The following pair received entry as lucky losers: Before the tournament During the tournament It was the 3rd title for Pe'er in her singles career.

It was the 1st title for both Bondarenko and Yakimova in their respective doubles careers.