[1][2] Despite being from Mexico –which is a member nation of CONCACAF and not CONMEBOL– Pachuca were eligible to compete in this tournament after winning the 2006 Mexican Primera División, earning them an invite from CONMEBOL and receiving an automatic berth directly to the knockout stages.

Pachuca's victory in the final marked the first time in history that a representative of CONCACAF won a CONMEBOL-sanctioned tournament.

[citation needed] This also marked the first time an Argentine team did not qualify to the Copa Sudamericana final, since the inaugural edition in 2002.

[citation needed] The final was played on a home-and-away two-legged basis, with Colo-Colo hosting the second leg.

The away goals rule was not applied, and extra time would be played if the aggregate score was tied after the second leg.