The 2006 FIU Golden Panthers football team represented Florida International University in the 2006 NCAA Division I FBS football season.

They participated as members of the Sun Belt Conference.

The Golden Panthers played their home games at the on-campus FIU Stadium in Miami, Florida.

The Golden Panthers finished the 2006 season winless in twelve games and were outscored by their opponents by a combined total of 313 to 115.

Their average of 9.6 points scored per game was the worst in the FBS that year.