The 2006 IPC Cycling World Championships were the 2nd World Championships for track and road cycling for athletes with a physical disability.

The Championships took place in Aigle, Switzerland from 11 to 18 September 2006, with track events on the first three days of competition, time trials on days 4 and 5, and road races on days 6 and 7.

Organised by the International Paralympic Committee, the event was the forerunner of the UCI organized Para-cycling Track and Road Championships, and the last to be organized by IPC Cycling; UCI took over the running of the event in 2007.

24 events were held on the track, while 34 events were held on the road.